Anti-Herpetic Activities of Chemical Components from the Brazilian Red Alga Plocamium Brasiliense

Author:

Ferreira Wilton José1,Amaro Rodrigo2,Cavalcanti Diana Negrão12,de Rezende Claudia Moraes3,Galvão da Silva Viveca Antonia Giongo2,Barbosa Juliana Eymara2,de Palmer Paixão Izabel Christina Nunes2,Teixeira Valéria Laneuville12

Affiliation:

1. Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal Fluminense, Niterói, RJ, Brazil

2. Programa de Pós-Graduação em Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense, P.O. Box 100.644, Niterói, RJ, 24001-970, Brazil

3. Departamento de Química Orgânica, Instituto de Química, Centro de Tecnologia, Bloco A, Universidade Federal do Rio de Janeiro, RJ, 22945-970, Brazil

Abstract

The CH2Cl2 crude extract and a fraction enriched with halogenated monoterpenes of the Brazilian red alga Plocamium brasiliense were evaluated for cytotoxicity and against the virus HSV-1. The extract showed low cytotoxicity compared with the fraction containing monoterpenes. The crude extract showed, in vitro, a high reduction of infectivity of the virus HSV-1.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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