Briarenol B, a New Polyoxygenated Briarane from the Octocoral Briareum excavatum-Reference-Cited by-同舟云学术

Briarenol B, a New Polyoxygenated Briarane from the Octocoral Briareum excavatum

Published:2017-02 Issue:2 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Li Mu-Jang¹,Su Yin-Di²,Liao Zuo-Jian²³,Wen Zhi-Hong³⁴,Su Jui-Hsin²⁵,Wu Yang-Chang⁶⁷⁸⁹,Sung Ping-Jyun²⁴⁵⁷⁹

Affiliation:

1. Antai Medical Care Corporation, Antai Tian-Sheng Memorial Hospital, Pingtung 928, Taiwan

2. National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan

3. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University & Academia Sinica, Kaohsiung 804, Taiwan

4. Department of Marine Biotechnology & Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan

5. Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan

6. School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan

7. Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan

8. Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan

9. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan

Abstract

A new polyoxygenated briarane diterpenoid, briarenol B (1), was isolated from the octocoral Briareum excavatum and its structure determined from spectroscopic data. In RAW264.7 cells, a macrophage-like murine cell line, briarane B (1) was found to enhance the protein expression of pro-inflammatory cyclooxygenase (COX-2) and inducible nitric oxide synthase (iNOS) in cells stimulated by lipopolysaccharide (LPS).

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200220

Reference17 articles.

1. Survey of Briarane-Type Diterpenoids of Marine Origin

2. Survey of Briarane-related Diterpenoids — Part II

3. Survey of Briarane-Type Diterpenoids — Part III

4. Survey of Briarane-Type Diterpenoids – Part IV

5. Briarane Diterpenoids Isolated from Gorgonian Corals between 2011 and 2013

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