A New Ursane-type Triterpenoid and Other Constituents from the Leaves of Crataegus azarolus var. aronia-Reference-Cited by-同舟云学术

A New Ursane-type Triterpenoid and Other Constituents from the Leaves of Crataegus azarolus var. aronia

Published:2016-11 Issue:11 Volume:11 Page:1934578X1601101
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Mahmud Sarbast A.¹,Al-Habib Omar A.M²,Bugoni Serena³,Clericuzio Marco⁴,Vidari Giovanni³

Affiliation:

1. Department of Biology, Faculty of Science, Soran University, Soran, Kurdistan Region-Iraq

2. Department of Biology, Faculty of Science, University of Zakho, Zakho, Kurdistan Region-Iraq

3. Dipartimento di Chimica and Centro CEMEC, Università di Pavia, Via Taramelli 12, 27100 Pavia, Italy

4. Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale, Via T. Michel 11, 15121 Alessandria, Italy

Abstract

A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601101103

Reference21 articles.

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2. Polyphenol Contents and Antioxidant Activities of Extracts from Flowers of Two Crataegus azarolus L. Varieties

3. The Investigation of Some Bioactive Compounds and Antioxidant Properties of Hawthorn (Crataegus monogyna subsp. monogyna jacq.)

4. Phytochemical characterization of several hawthorn (Crataegus spp.) species sampled from the Eastern Mediterranean region of Turkey

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