Dihydroflavonol and Flavonol Derivatives from Macaranga Recurvata-Reference-Cited by-同舟云学术

Dihydroflavonol and Flavonol Derivatives from Macaranga Recurvata

Published:2012-10 Issue:10 Volume:7 Page:1934578X1200701
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Tanjung Mulyadi¹,Hakim Euis H.²,Elfahmi ³,Latip Jalifah⁴,Syah Yana M.²

Affiliation:

1. Chemistry Department, Airlangga University, Jalan Darmawangsa Dalam, Surabaya 60222, Indonesia

2. Organic Chemistry Division, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia

3. School of Pharmacy, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia

4. Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

Abstract

Two new dihydroflavonol derivatives, macarecurvatins A and B, have been isolated from the leaves of Macaranga recurvata(Euphorbiaceaae), along with the known compounds diisoprenylaromadendrin, glyasperin A and broussoflavonol F. The structures of the new compounds were determined on the basis of spectroscopic evidence. Upon cytotoxic evaluation against P-388 cells, macarecurvatin B showed strong activity with an IC50 of 0.83 μM.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1200701013

Reference9 articles.

1. Isoprenylated Flavanones and Dihydrochalcones from Macaranga Trichocarpa

2. Macagigantin, a farnesylated flavonol from Macaranga gigantea

3. Phenolic Derivatives with an Irregular Sesquiterpenyl Side Chain from Macaranga pruinosa

4. Geranylated Flavonols from Macaranga Rhizinoides

5. More Phenolic Derivatives with an Irregular Sesquiterpenyl Side Chain from Macaranga pruinosa

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1. Macagigantin A, A New Flavonoid from Macaranga gigantea (Rchb.f & Zoll.) Mull.Arg;Natural Product Sciences;2023-12-31

2. Prenylated 9,10-dihydrophenanthrenes from Macaranga javanica;Zeitschrift für Naturforschung B;2015-07-02