Distribution and Diversity of Usage of the Amaryllidaceae in the Traditional Remediation of Infectious Diseases

Author:

Nair Jerald J.1,van Staden Johannes2,Bonnet Susanna L.1,Wilhelm Anke1

Affiliation:

1. Department of Chemistry, University of the Free State, 205 Nelson Mandela Drive, Bloemfontein, 9301, South Africa

2. Research Centre for Plant Growth and Development, School of Life Sciences, University of KwaZulu-Natal Pietermaritzburg, Private Bag X01, Scottsville 3209, South Africa

Abstract

Globalization and multidrug resistance are amongst the factors implicated in the resurgence of infectious diseases in recent years. This has fostered a compelling need in drug discovery to replace (or supplement) existing schedules. The floral biodiversity has been identified as a viable resource platform due to its inimitable chemical characteristics as well as the presence of numerous of its members in traditional medicinal approaches towards these diseases. Whilst the plant family Amaryllidaceae is conventionally associated with cancer and motor-neuron disease therapies, this survey shows that it has a significant presence in the remediation of infections and infection-related ailments. This verifiable indigenous knowledge could amplify efforts towards the identification of the active chemical constituents.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference72 articles.

1. EwaldPW. (1994) Evolution of Infectious Disease. Oxford University Press, New York

2. ByrneJP. (2006) Daily Life During the Black Death. Greenwood Press, Westport, Connecticut

3. 1918 Influenza: the Mother of All Pandemics

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