Antimicrobial Constituents from Allium Hookeri Root

Author:

Kim Jung-Eun1,Seo Ji-Hye2,Bae Min-Suk3,Bae Chun-Sik4,Yoo Jin-Cheol5,Bang Mi-Ae6,Cho Seung-Sik1,Park Dae-Hun2

Affiliation:

1. Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan, Jeonnam 534729, Korea

2. Department of Oriental Medicine Materials, Dongshin University, Naju, Jeonnam 520714, Korea

3. Department of Environmental Engineering, Mokpo National University, Muan, Jeonnam 534729, Korea

4. College of Veterinary Medicine, Chonnam National University, Gwangju 500757, Korea

5. Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501759, Korea

6. Research Development Team, Jeonnam Biofood Technology Center, Naju520330, Korea

Abstract

In this study, we partially purified the ethyl acetate soluble fraction of the ethanol extract of the root of Allum hookeri. We identified seven compounds, benzoic acid, tetradecanoic acid, hexadecanoic acid, ferulic acid, cinnamic acid, octadecanoic acid and hexanedioic acid, that have antimicrobial activity using GC-MS, and evaluated the antimicrobial susceptibility and MIC (minimum inhibitory concentration) against multidrug-resistant bacteria.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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