Multisystem inflammatory syndromeneonates (MIS-N) associated with acute kidney injury: A case report

Abstract

A late preterm presented with multisystem involvement (respiratory failure, shock, acute kidney injury). Initially, the baby was managed with mechanical ventilation, inotropic support, antibiotics, fluid restriction and furosemide infusion. Despite conservative management for 12 h, urine output, metabolic status and renal function did not improve; peritoneal dialysis was therefore commenced. Intravenous immunoglobulin and methylprednisolone were introduced. Respiratory failure, shock and acute kidney injury (AKI) then resolved. The baby’s condition gradually improved, and he was discharged after 19 days. On follow up, he was gaining weight satisfactorily, with no sequalae. Atypical presentation of multisystem involvement in the form of AKI should not be missed since it is treatable with definitive and supportive care and has a favorable outcome.