Leptospirosis: a diagnostic conundrum-Reference-Cited by-同舟云学术

Leptospirosis: a diagnostic conundrum

Published:2018-08-19 Issue:4 Volume:48 Page:306-309
ISSN:0049-4755
Container-title:Tropical Doctor
language:en
Short-container-title:Trop Doct

Author:

Gurumurthy Keerthivasan¹^ORCID,Narasimha Harish Belgode²,Wyawahare Mukta³,Biswal Niranjan⁴

Affiliation:

1. Assistant Professor, Department of Microbiology, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India

2. Senior Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India

3. Associate Professor, Department of General Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India

4. Professor, Department of Paediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India

Abstract

Leptospirosis is a serious public health concern worldwide. It is highly endemic in the Andaman Islands and its prevalence is increasing in other Indian states. Clinical features are non-specific and diagnosis relies on laboratory confirmation. The gold standard is microscopic agglutination testing, but this is not widely available. Real-time polymerase chain reaction testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body. We found it to be 100% specific, but it should be used in the first 10 days of illness for reliable results.

Publisher

SAGE Publications

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/0049475518788470

Reference19 articles.

1. Leptospirosis

2. A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp

3. The globalization of leptospirosis: worldwide incidence trends

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