Filariasis presenting with bicytopenia, progressive splenomegaly and acute renal failure: An unusual case report

Author:

Agarwal Kiran1,Gaur Kavita2ORCID,Khasim Nazma3

Affiliation:

1. Director Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India

2. Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India

3. Post Graduate Resident, Department of Pathology, Lady Hardinge Medical College, New Delhi, India

Abstract

Extra-lymphatic manifestation of filariasis, especially as acute renal failure, is uncommon and may be clinically unsuspected. We document the case of a 60 year old elderly male who presented with bilateral pedal oedema, fatigue and abdominal distension. Investigations revealed severe anaemia, splenomegaly and acute renal failure. Bone marrow aspiration was performed to evaluate the clinical suspicion of malignancy. Out of eight smears examined, microfilaria ( Brugia malayi) were identified in two. This presentation was devoid of peripheral eosinophilia. The patient was commenced on a regimen of diethylcarbamazine, on which he made a good recovery. The incidence of extra-lymphatic filariasis is largely unknown and sparsely reported. Such a presentation should be kept in mind by both clinicians and pathologists as it is potentially treatable.

Publisher

SAGE Publications

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

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