Screening of toxoplasmosis in cancer patients: a concern

Author:

Abdoli Amir12ORCID,Barati Mohammad3,Pirestani Majid4,Dalimi Abdolhossein5

Affiliation:

1. Assistant professor, Department of Parasitology and Mycology, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran

2. Assistant professor, Research Center for Noncommunicable Diseases, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran

3. Assistant professor, Infectious Diseases Research Center, AJA University of Medical Sciences, Tehran, Iran

4. Assistant professor, Department of Parasitology, Faculty of Medical Sciences, TarbiatModares University, Tehran, Iran

5. Professor, Department of Parasitology, Faculty of Medical Sciences, TarbiatModares University, Tehran, Iran

Abstract

Toxoplasmosis is an opportunistic infectious disease in immunocompromised patients, including cancer patients, whose detection is by molecular and serological methods. A total of 106 blood samples from patients with different types of cancer were evaluated for anti- Toxoplasma gondii IgG and IgM antibodies by the enzyme-linked immunosorbent assay (ELISA) and the parasite DNA by nested polymerase chain reaction (PCR). These were detected in 41.51% (44/106) and 0.94% (1/106), respectively, but T. gondii IgM antibody was not detected at all. These results suggest that the screening of toxoplasmosis should be considered more routinely in cancer patients.

Funder

AJA University of Medical Sciences

Publisher

SAGE Publications

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

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