Epidemiology, clinical, and laboratory profile of patients with hepatitis C: A prospective, observational study from north-eastern India-Reference-Cited by-同舟云学术

Epidemiology, clinical, and laboratory profile of patients with hepatitis C: A prospective, observational study from north-eastern India

Published:2022-07-13 Issue:4 Volume:52 Page:484-488
ISSN:0049-4755
Container-title:Tropical Doctor
language:en
Short-container-title:Trop Doct

Author:

Barman Bhupen¹^ORCID,Roy Akash²^ORCID,Nune Arvind³,Lyngdoh W. Valarie⁴,Jamil Md¹,Tiewsoh Iadarilang⁵

Affiliation:

1. Associate Professor, Department of General Medicine, North Eastern Indira Gandhi Regional Institute of health and Medical sciences, Shillong, India

2. Assistant Professor, Department of Hepatology (HPB and Liver Transplant Unit), Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow

3. Consultant Rheumatologist and General Physician, Southport and Ormskirk NHS Trust, Southport, UK

4. Associate Professor, Department of Microbiology, North Eastern Indira Gandhi Regional Institute of health and Medical sciences, Shillong, India

5. Assistant Professor, Department of General Medicine, North Eastern Indira Gandhi Regional Institute of health and Medical sciences, Shillong, India

Abstract

Low and middle-income countries (LMICs) contribute to 80% of the global hepatitis C virus (HCV) infection burden. Intravenous drug use (IVDU) is not uncommon in Northeastern India, thus contributing to HCV. Its epidemiology, clinical, and laboratory profile were studied in a tertiary care centre in northeastern India.HCV patients (age >18) of either sex were prospectively assessed for demographic, virological, and genotype distributions. Most were male (M: F, 5.8:1) with a mean age of 37.1 ± 11.8 years. The most common risk factor was IVDU(77.69%), followed by concomitant alcohol use in 69.2%. Besides genotype 3 (59.2%), genotype 1 (26.1%) and genotype 6 were also common (14.6%). The demographics, liver disease severity, and biochemical parameters were similar across genotypes.

Publisher

SAGE Publications

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/00494755221110636

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