Affiliation:
1. Department of Biological Sciences, University of Bradford, Bradford, BD7 1DP, England
Abstract
A survey of the literature shows that although poliovirus may be recovered from fetuses whose mothers have paralytic poliomyelitis, there is no evidence that the fetuses themselves are affected. It is suggested that if postnatal poliomy elitis results from an autoallergic response not developed in the fetus, then poliovirus cannot enter the CNS of the fetus. When a mother has paralytic poliomyelitis at delivery the neonate has a 40 per cent chance of poliomyelitis, with a case fatality rate of about 50 per cent. It is suggested that most of these neonates become infected by virus entry into the exposed olfactory and nasal nerve endings after the membranes have burst. This would explain the very short incubation period and the high case and case fatality rates.
Subject
Pediatrics, Perinatology, and Child Health
Cited by
8 articles.
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1. Enterovirus and parechovirus infections;Remington and Klein's Infectious Diseases of the Fetus and Newborn Infant;2025
2. Perinatal Enterovirus Infections;Human Enterovirus Infections;2014-04-09
3. Enterovirus and Parechovirus Infections;Infectious Diseases of the Fetus and Newborn;2011
4. Enterovirus and Parechovirus Infections;Infectious Diseases of the Fetus and Newborn Infant;2006
5. Enterovirus;Clinical Perspectives in Obstetrics and Gynecology;1994