Spontaneous Recovery of Selective IgA Deficiency

Author:

Blum Paul M.1,Hong Richard2,Stiehm E. Richard1

Affiliation:

1. Division of Immunology/Allergy, Department of Pediatrics, UCLA Schoal of Medicine, Los Angeles, California

2. Division of Immunology, Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin

Abstract

Patients with selective IgA deficiency, the most common primary immuno deficiency, occasionally may undergo spontaneous recovery. In this paper we present three additional children whose IgA levels spontaneously returned to normal. All three presented with gastrointestinal symptoms, and one child also had frequent upper respiratory infections. We review other cases of spontaneous IgA deficiency, and the role of exogenous function in its etiology, and possible mechanisms of recovery.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology, and Child Health

Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The long and winding road to IgA deficiency: causes and consequences;Expert Review of Clinical Immunology;2016-10-25

2. Isotype Defects;Stiehm's Immune Deficiencies;2014

3. Selective IgA deficiency in early life: Association to infections and allergic diseases during childhood;Clinical Immunology;2009-10

4. The Four Most Common Pediatric Immunodeficiencies;Journal of Immunotoxicology;2008-01

5. The clinical significance of immunoglobulin A deficiency;Annals of Clinical Biochemistry: International Journal of Laboratory Medicine;2007-03-01

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