Preterm Premature Rupture of Membranes: Clinical Outcomes of Late-Preterm Infants

Author:

Mateus Julio1,Fox Karin2,Jain Sangeeta2,Jain Sunil3,Latta Richard4,Cohen Jerry4

Affiliation:

1. Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA,

2. Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA

3. Department of Pediatric Neonatology, University of Texas Medical Branch, Galveston, TX, USA

4. Department of Obstetrics and Gynecology, Abington Memorial Hospital, Abington, PA, USA

Abstract

Objective: To determine gestational age-specific neonatal outcomes of late preterm infants delivered as a consequence of premature rupture of membranes (PROM). Methods: Retrospective cohort study of infants born to women delivered electively due to preterm PROM between 340/7 and 366/7 weeks of gestation. Neonatal outcomes were compared between those delivered at 340/7 to 34 6/7 weeks, at 350/7 to 356/7 weeks, and at 36 0/7 to 366/7 weeks. Results: 192 infants were identified. The 340/7 to 346/7 week infants had significantly higher neonatal intensive care admission rate (72.5%) compared to those at 35 0/7 to 356/7 weeks (22.8%) and at 36 to 366/7 weeks (17.8%) ( P < .05). Neonatal respiratory distress syndrome was significantly higher at 340/7 to 346/7 weeks (35.4%) compared with 350/7 to 356/7 week and 360/7 to 36 6/7 week infants (10.5% and 4.1%; P < .05). The longest hospitalization occurred in the 340/7 to 346/7 week infants (248.5 ± 20.0 hours). Conclusion: Substantial short-term morbidity occurred in late preterm infants. The greatest number of complications affected infants born at 340/7 to 346/7 weeks.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology and Child Health

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