Sclerosis of the Mastoid Air Cells as an Indicator of Undiagnosed Otitis Media in Children With Down's Syndrome

Author:

Roizen Nancy J.1,Martich Vesna2,Ben-Ami Tamar3,Shalowitz Madeleine U.4,Yousefzadeh David K.2

Affiliation:

1. University of Chicago Pritzker School of Medicine, La Rabida Children's Hospital and Research Center, Chicago, Illinois, Wyler Children's Hospital, Chicago, Illinois

2. Cincinnati Children's Hospital, Cincinnati, Ohio

3. Wyler Children's Hospital, Chicago, Illinois

4. University of Chicago Pritzker School of Medicine, La Rabida Children's Hospital and Research Center, Chicago, Illinois

Abstract

We hypothesized that many children with Down's syndrome have undiagnosed otitis media. In a 1989 study of lateral neck radiographs of 22 children with Down's syndrome, we found that 64% had sclerosis of the mastoid air cells, indicating untreated or inadequately treated otitis media. We reviewed the lateral neck radiographs of 53 children with Down's syndrome and interviewed their parents regarding the diagnosis of otitis media. Mastoid air cells were found to be sclerotic in 22 (42%) of study subjects; 32% of these had no known history of otitis media. For the 68% of children diagnosed as having had otitis media, the most common symptoms were fever (61 % ) and cough or coryza (58%). Sclerosis of the mastoid processes was not associated with a high frequency of otitis media (>20 episodes) or a higher frequency of hearing loss, but was associated with subsequent myringotomy and insertion of a ventilatory tube (P= .038). Our finding of sclerotic mastoids in 42% of children with Down's syndrome raises the possibility that children with Down's syndrome have unidentified or inadequately treated episodes of otitis media.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology and Child Health

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1. Barriers to timely tympanostomy tube placement in trisomy 21;International Journal of Pediatric Otorhinolaryngology;2021-01

2. Hearing loss in Down Syndrome revisited – 15 years later;International Journal of Pediatric Otorhinolaryngology;2016-09

3. A general review of the otolaryngologic manifestations of Down Syndrome;International Journal of Pediatric Otorhinolaryngology;2014-06

4. Outcomes of tympanostomy tube placement in children with Down syndrome—A retrospective review;International Journal of Pediatric Otorhinolaryngology;2014-02

5. Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media;Mammalian Genome;2013-09-26

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