Fatal Overdose from Bendectin

Author:

Bayley Marianne1,Walsh Lieutenant F. M.1,Valaske Captain M. J.1

Affiliation:

1. Toxicology Section, Department of Laboratory Medicine, National Naval Medical Center, Bethesda, Md. 20014

Abstract

A three-year-old male ingested approximately 100 tablets of Bendectin. He developed tonic- clonic seizures followed by cardiac arrest. Tox icologic analysis yielded high levels of doxyl amine, dicyclomine, and pyridoxine in blood, peritoneal fluid, and tissue homogenates. The antihistamine, doxylamine succinate appears to be the toxic constituent. Analytical methods used to document the case are herein described. described.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology, and Child Health

Reference5 articles.

1. Poisoning from delayed release tablets.

2. Department of Medical Research Notebook 124B. Cincinnati, Ohio, Merrell National Laboratories, pp. 8-91.

3. THE TOXIC EFFECTS OF ANTI-HISTAMINIC DRUGS

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