A Complication of Phototherapy in the Newborn: The “Bronze Baby”

Author:

Sharma RAJ K.12,Ente GERALD13,Collipp PLATON J.14,Maddaiah VADDANAHALLY T.15,Rezvani IRAJ16

Affiliation:

1. Department of Pediatrics, Nassau County Medical Center, East Meadow, N. Y. 11554.

2. Instructor in Pediatrics, Stony Brook Health Sciences Center.

3. Clinical Director of Neonatology.

4. Department of Pediatrics, Professor of Pediatrics, Stony Brook Health Sciences Center.

5. Research Biochemist.

6. Pediatric Research Fellow.

Abstract

A newborn infant had an unusual reversible complication caused by light therapy for hyperbilirubinemia. A dark grey-brown color of the skin, urine, and serum developed on the fifth day, after 24 hours of light therapy. Serum bilirubin (direct and total), SGOT, and LDH were elevated. The infant recovered, and bilirubin and enzymes returned to normal after a period of three weeks. A possible pathologic mechanism for this complication is suggested.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology, and Child Health

Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Testicular Changes in Newborn Rats Exposed to Phototherapy;Pediatric and Developmental Pathology;1999-07

2. Bronze Baby Syndrome: An Animal Model;Pediatric Research;1990-01

3. Hyperbiliverdinemia in the bronze baby syndrome;Journal of the American Academy of Dermatology;1987-01

4. Bronze baby syndrome, biliary hypoplasia, incomplete Beckwith-Wiedemann syndrome and partial trisomy 11;European Journal of Pediatrics;1986-04

5. Management of Unconjugated Hyperbilirubinemia in the Newborn;Seminars in Liver Disease;1983-02

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