Serum immunoglobulin G Subclasses in Patients During Acute Hepatitis A-Reference-Cited by-同舟云学术

Serum immunoglobulin G Subclasses in Patients During Acute Hepatitis A

Published:1990-08 Issue:8 Volume:29 Page:471-473
ISSN:0009-9228
Container-title:Clinical Pediatrics
language:en
Short-container-title:Clin Pediatr (Phila)

Author:

Muller Christian¹,Godl Irene²,Leibl Heinz³,Eibl Martha M.⁴

Affiliation:

1. . Department of Gastroenterology and Hepatology

2. Kinderinfektionsabteilung, Wilhelminenspital, Vienna

3. Immuno AG, Vienna, Austria

4. Institute of Immunology, University of Vienna

Abstract

IgG subclasses were measured in sera of 47 patients with acute hepatitis A during the course of the disease. IgG1 and IgG3 serum levels were found to be elevated, whereas IgG2 and IgG4 subclass concentrations did not differ from that found in healthy control individuals. These findings indicate that, similar to the specific antiviral antibody, the polyclonal increase of serum concentrations of IgG in acute hepatitis A is not equally distributed to all IgG subclasses but is restricted to IgGl and IgG3.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology and Child Health

Link

http://journals.sagepub.com/doi/pdf/10.1177/000992289002900811

Reference10 articles.

1. IMMUNOGLOBULINS IN THE COURSE OF VIRAL HEPATITIS AND IN CHOLESTATIC AND OBSTRUCTIVE JAUNDICE

2. Quantitative determination of single serum proteins during acute hepatitis in childhood

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1. Serum immunoglobulin G subclass responses in different phases of hepatitis E virus infection;Journal of Medical Virology;2013-03-18

2. Increased serum immunoglobulin G1 levels in hepatitis C virus infection;Hepatology;1995-06

3. Immunopathology of Hepatitis A and Hepatitis E Virus Infections;Immunology of Liver Disease;1994