Chronological and Clinical Characteristics of Apnea Associated With Respiratory Syncytial Virus Infection: A Retrospective Case Series

Author:

Arms Joseph Leo1,Ortega Henry2,Reid Samuel2

Affiliation:

1. Division of Emergency Medicine, Children's Hospitals and Clinics of Minnesota, Minneapolis,

2. Division of Emergency Medicine, Children's Hospitals and Clinics of Minnesota, Minneapolis

Abstract

Objective Infants with respiratory syncytial virus (RSV) infection are at risk for developing apnea. The authors compared patients with RSV infection who develop apnea with those who do not, to help ambulatory physicians risk stratify their patients with RSV infection. Methods Entry criteria were age less than 1 year, RSV infection, and presentation to the authors' pediatric emergency departments. Random and weighted sampling techniques were used to identify the study group and provide the control sample. Charts were abstracted for 34 clinical variables. Results The study group consisted of 42 patients with apnea, and the control group consisted of 198 patients without apnea. Logistic regression analysis identified 2 independent variables associated with apnea: young age and presentation with apnea. Most patients with apnea were less than 2 months of age and were ill for less than 5 days. Conclusions Age and duration of illness may help clinicians determine which previously healthy infants are at risk for apnea.

Publisher

SAGE Publications

Subject

Pediatrics, Perinatology and Child Health

Reference19 articles.

1. McIntosh K. Respiratory syncytial virus. In: Behrman RE , Kliegman RM, Jenson HB, eds. Nelson Textbook of Pediatrics . 16th ed. Philadelphia, PA: W. B. Saunders; 2004:991-993.

2. Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

3. Diagnosis and Management of Bronchiolitis

4. Apnea associated with respiratory syncytial virus infection in young infants

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