Gastric Neuroendocrine Tumor Treatment and Survival Outcome Depends on Facility Type

Author:

Platoff Rebecca M.1,Lou Johanna1,Bush Kathryn2,Zhu Clara1,Spitz Elizabeth1,Gaughan John P.12,Atabek Umur13,Spitz Francis13,Hong Young K13

Affiliation:

1. Department of Surgery, Cooper University Hospital, Camden, NJ, USA

2. School of Medicine, Cooper Medical School of Rowan University, Camden, NJ, USA

3. MD Anderson Cancer Center at Cooper University Hospital, Camden NJ, USA

Abstract

Background Gastric neuroendocrine tumors (gNETs) are rare cancers for which surgery may improve survival. We aim to determine if facility type affects treatment and survival outcomes. Methods The NCDB was queried for patients with gNET from 2004-2016 and stratified into Academic/Research Program (ARP), Community Cancer Program (CCP), Comprehensive Community Cancer Program (CCCP), or Integrated Network Cancer Program (INCP). Overall survival along with clinical and demographic features was compared. Results Median survival was improved in patients treated at an academic program: 137.3 months versus 88.0, 96.3, and 100.2 for CCP, CCCP, INCP, respectively (P < .0001). Patients treated at academic centers were more likely to have surgery (64.2% vs 59.1%, 57.5%, 51.4%, P < .0001). After propensity matching for age, race, grade, stage, insurance status, and comorbidity score, survival benefit from treatment at an academic center remained (P = .03), particularly for patients undergoing surgery (P < .0001) and chemotherapy (P = .04). Conclusion Patients with gNET treated at an academic hospital had improved median survival after propensity matching and may benefit from treatment at academic rather than community medical centers.

Publisher

SAGE Publications

Subject

General Medicine

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