Surgical Considerations for the Familial Cancer Syndrome, Neurofibromatosis 1: A Comprehensive Review-Reference-Cited by-同舟云学术

Surgical Considerations for the Familial Cancer Syndrome, Neurofibromatosis 1: A Comprehensive Review

Published:2009-02 Issue:2 Volume:75 Page:120-128
ISSN:0003-1348
Container-title:The American Surgeon
language:en
Short-container-title:The American Surgeon

Author:

Slam Kristine D.¹,Bohman Summer L.²,Sharma Rupa³,Chaudhuri Prabir K.⁴

Affiliation:

1. Departments of Surgery and Toledo, Ohio

2. Pathology, University of Toledo, Toledo, Ohio

3. Medical School, University of Toledo, Toledo, Ohio

4. Division of Surgical Oncology, University of Toledo, Toledo, Ohio

Abstract

Neurofibromatosis 1 is one of the more common in heritable disorders that surgeons may encounter. A plethora of systemic associations, both benign and malignant, can affect these patients, and an acute awareness of these associations is essential for proper surgical care. A complete review of this disorder from the surgical perspective follows, highlighting the importance of this awareness. A brief review on the management and follow-up of surgical malignancies associated with this disorder is included.

Publisher

SAGE Publications

Subject

General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000313480907500203

Reference75 articles.

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3. The neurofibromatosis type 1 gene encodes a protein related to GAP

4. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

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