Hypercoagulable Factors Attributing to Superior Mesenteric Vein Thrombosis and Acute Mesenteric Ischemia

Author:

Van Horn Alexandra L.1ORCID,Soult Alexa P.1

Affiliation:

1. Department of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA

Abstract

Acute mesenteric ischemia is rare and can be difficult to diagnose due to vague symptoms often endorsed by patients. It can be fatal if not discovered in time, as it can lead to bowel ischemia, sepsis, and ultimately death. Here, we present a case of a 23-year-old female with hepatic steatosis, obesity, and 5-year history of birth control use who developed acute mesenteric ischemia secondary to superior mesenteric venous (SMV) thrombosis, requiring small bowel resection of 238 cm out of 480 cm (49.5%) after delay in diagnosis. Hypercoagulable and genetic workup during admission later revealed heterozygous factor V Leiden (FVL) mutation. The patient was ultimately discharged to inpatient rehabilitation on anticoagulation.

Publisher

SAGE Publications

Subject

General Medicine

Reference4 articles.

1. Sulger E, Dhaliwal HS, Goyal A, Gonzalez L. Mesenteric venous thrombosis – statpearls – NCBI bookshelf. National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK459184/. Published July 18, 2022. Accessed September 25, 2022.

2. Guillen B, Atherton NS. Short bowel syndrome – statpearls – NCBI bookshelf. National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK536935/#:∼:text=Short-bowel-syndrome%20(SBS)-in,for-nutritional-and-fluid-supplements. Published July 26, 2022. Accessed September 25, 2022.

3. Oral contraceptive and acute intestinal ischemia with mesenteric venous thrombosis: a case report

4. Mesenteric vein thrombosis in a patient heterozygous for factor V Leiden and G20210A prothrombin genotypes

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