Comparable 2-Year Restenosis Rates Following Subintimal and Intraluminal Drug-Eluting Stent Implantation for Femoropopliteal Chronic Total Occlusion

Author:

Ishihara Takayuki1,Takahara Mitsuyoshi23,Iida Osamu1,Soga Yoshimitsu4,Hirano Keisuke5,Yamauchi Yasutaka6,Zen Kan7,Kawasaki Daizo8,Nanto Shinsuke9,Yokoi Hiroyoshi10,Uematsu Masaaki1,

Affiliation:

1. Kansai Rosai Hospital Cardiovascular Center, Hyogo, Japan

2. Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

3. Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

4. Department of Cardiology, Kokura Memorial Hospital, Fukuoka, Japan

5. Division of Cardiology, Saiseikai Yokohama-City Eastern Hospital, Kanagawa, Japan

6. Cardiovascular Center, Kikuna Memorial Hospital, Kanagawa, Japan

7. Department of Cardiovascular Medicine, Omihachiman Community Medical Center, Shiga, Japan

8. Cardiovascular Division, Department of Internal Medicine, Morinomiya Hospital, Osaka, Japan

9. Nishinomiya Municipal Central Hospital, Hyogo, Japan

10. Cardiovascular Center, Fukuoka Sanno Hospital, Fukuoka, Japan

Abstract

Purpose: To report midterm outcomes after subintimal vs intraluminal drug-eluting stent (DES) implantation for femoropopliteal (FP) chronic total occlusion (CTO). Methods: This subanalysis of the prospective, multicenter ZEPHYR study (ZilvEr PTX for tHe Femoral ArterY and Proximal Popliteal ArteRy) included 176 patients (mean age 74±8 years; 130 men) with 192 de novo FP CTOs that were evaluated by intravascular ultrasound after successful guidewire crossing. The primary outcome was the 2-year restenosis rate after subintimal (n=73) or intraluminal (n=119) DES implantation. Propensity score matching extracted 61 matched pairs (mean age 75 years; 49 men) for patency analysis to minimize baseline intergroup differences. Restenosis rates are reported with the 95% confidence interval (CI). Results: The 1-year restenosis rates in the groups with subintimal and intraluminal DES implantation were 45% (95% CI 32% to 59%) and 35% (95% CI 22% to 49%), respectively (p=0.352), whereas the corresponding rates at 2 years were not significantly different (p=0.648) at 56% (95% CI 41% to 71%) and 51% (95% CI 34% to 68%). Baseline characteristics had no significant interaction effect on the association of subintimal angioplasty with restenosis risk. Conclusion: In FP CTO, 2-year restenosis rates were comparable after subintimal or intraluminal DES implantation.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging,Surgery

Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3