Crossing barriers: the burden of inflammatory bowel disease across Western Europe

Author:

Kumar Aditi1ORCID,Yassin Nuha2,Marley Alexandra3,Bellato Vittoria4,Foppa Caterina56,Pellino Gianluca78,Myrelid Pär910,Millan Monica11,Gros Beatriz1213,Avellaneda Nicolas14,Catalan-Serra Ignacio151617,El-Hussuna Alaa18,Cunha Neves João A.1920,Roseira Joana1920ORCID,Cunha Miguel F.2021,Verstockt Bram2223,Bettenworth Dominik2425,Mege Diane26,Brookes Matthew J.327

Affiliation:

1. Department of Gastroenterology, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Birmingham, UK B15 2GW

2. Department of Colorectal Surgery, University Hospitals Birmingham, Birmingham, UK

3. Department of Gastroenterology, The Royal Wolverhampton NHS Trust, Wolverhampton, UK

4. Department of Minimally Invasive Surgery, University of Rome ‘Tor Vergata’, Rome, Italy

5. Department of Biomedical Sciences, Humanitas University, Milan, Italy

6. Division of Colon and Rectal Surgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy

7. Colorectal Surgery, Vall D’Hebron University Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain

8. Department of Advanced Medical and Surgical Sciences, Universita degli Studi della Campania ‘Luigi Vanvitelli’, Naples, Italy

9. Department of Surgery, Linköping University Hospital, Linköping, Sweden

10. Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden

11. Department of Surgery, La Fe University and Polytechnic Hospital, University of Valencia, Valencia, Spain

12. Department of Gastroenterology and Hepatology, Reina Sofia University Hospital, Cordoba, Spain

13. Edinburgh IBD Unit, Western General Hospital, Edinburgh, UK

14. General and Colorectal Surgery Department, CEMIC University Hospital, Buenos Aires, Argentina

15. Department of Gastroenterology, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway

16. Department of Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway

17. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway

18. Open Source Research Organisation, Aalborg, Denmark

19. Department of Gastroenterology, Algarve University Hospital Centre, Portimão, Portugal

20. Algarve Biomedical Centre, University of Algarve, Faro, Portugal

21. Department of Colorectal Surgery, Algarve University Hospital Centre, Portimão, Portugal

22. Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Belgium

23. Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium

24. CED Schwerpunktpraxis, Münster, Germany

25. Medical Faculty, University of Münster, Münster, Germany

26. Department of Digestive and Oncology Surgery, Timone University Hospital, Marseille, France

27. School of Medicine and Clinical Practice, Faculty of Sciences and Engineering, University of Wolverhampton, Wolverhampton UK

Abstract

An estimated 2.5–3 million individuals (0.4%) in Europe are affected by inflammatory bowel disease (IBD). Whilst incidence rates for IBD are stabilising across Europe, the prevalence is rising and subsequently resulting in a significant cost to the healthcare system of an estimated 4.6–5.6 billion euros per year. Hospitalisation and surgical resection rates are generally on a downward trend, which is contrary to the rising cost of novel medication. This signifies a large part of healthcare cost and burden. Despite publicly funded healthcare systems in most European countries, there is still wide variation in how patients receive and/or pay for biologic medication. This review will provide an overview and discuss the different healthcare systems within Western Europe and the barriers that affect overall management of a changing IBD landscape, including differences to hospitalisation and surgical rates, access to medication and clinical trial participation and recruitment. This review will also discuss the importance of standardising IBD management to attain high-quality care for all patients with IBD.

Publisher

SAGE Publications

Subject

Gastroenterology

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