Geroscience: Aging and Oral Health Research

Author:

Weintraub J.A.1ORCID,Kaeberlein M.2,Perissinotto C.3,Atchison K.A.4,Chen X.5ORCID,D’Souza R.N.6ORCID,Feine J.S.7,Ghezzi E.M.8ORCID,Kirkwood K.L.910ORCID,Ryder M.11,Slashcheva L.D.12ORCID,Touger-Decker R.13ORCID,Wu B.14ORCID,Kapila Y.15

Affiliation:

1. Department of Pediatric and Public Health, Adams School of Dentistry University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

2. Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA

3. Division of Geriatrics, School of Medicine, University of California San Francisco, San Francisco, CA, USA

4. Section of Public and Population Health, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, USA

5. Division of Restorative and Prosthetic Dentistry, College of Dentistry, The Ohio State University College of Dentistry, Columbus, OH, USA

6. NIDCR, NIH, DHHS, Bethesda, MD, USA

7. Population Health, Faculty of Dental Medicine and Oral Health Sciences, McGill University, Quebec, Canada

8. Department of Cariology, Restorative Sciences & Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

9. Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY, USA

10. Department of Head & Neck/Plastic & Reconstructive Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA

11. Division of Periodontology, Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, San Francisco, CA, USA

12. Apple Tree Dental, Research Director, Innovations Team, Corporate Office, Fergus Falls, MN, USA

13. Department of Diagnostic Sciences, Rutgers School of Dental Medicine, School of Health Professions, Rutgers State University of New Jersey, Newark, NJ, USA

14. Rory Meyers College of Nursing, New York University, New York, NY, USA

15. Biosystems and Function and Periodontics, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, USA

Abstract

Research in aging has significantly advanced; scientists are now able to identify interventions that slow the biologic aging processes (i.e., the “hallmarks of aging”), thus delaying the onset and progression of multiple diseases, including oral conditions. Presentations given during the 3-part session “Geroscience: Aging and Oral Health Research,” held during the 2023 American Association for Dental, Oral, and Craniofacial Research meeting, are summarized in this publication. Speakers’ topics spanned the translational research spectrum. Session 1 provided an overview of the geroscience and health span (disease-free and functional health throughout life) concepts. The common molecular mechanisms between oral cancer and aging were discussed, and research was presented that showed periodontal microflora as a potential factor in Alzheimer’s disease progression. Session 2 focused on behavioral and social science aspects of aging and their oral health significance. The keynote provided evidence that loneliness and isolation can have major health effects. These social conditions, along with poor oral health, tooth loss, and cognitive decline, could potentially affect healthy eating ability and systemic health in older adults. Research could help elucidate the directions and pathways connecting these seemingly disparate conditions. Session 3 focused on the delivery of oral care in different settings and the many barriers to access care faced by older adults. Research is needed to identify and implement effective technology and strategies to improve access to dental care, including new delivery and financing mechanisms, workforce models, interprofessional provider education and practice, and use of big data from medical–dental integration of electronic health records. Research to improve the “oral health span,” reduce oral health disparities, and increase health equity must be tackled at all levels from biologic pathways to social determinants of health and health policies.

Publisher

SAGE Publications

Subject

General Medicine

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