TT Virus Infection: Role of Interferons, Interleukin-28 and 29, Cytokines and Antiviral Proteins-Reference-Cited by-同舟云学术

TT Virus Infection: Role of Interferons, Interleukin-28 and 29, Cytokines and Antiviral Proteins

Published:2007-04 Issue:2 Volume:20 Page:249-258
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Garbuglia A.R.,Grasso F.¹,Donà M.G.¹,Mochi S.¹,Conti P.²,De Lutiis M.A.³,Giorgi C.¹,Iezzi T.⁴

Affiliation:

1. Instituto Superiore di Sanità, Department of Infectious Parasitic and Immunomediated Diseases, Rome

2. Department of Oncology and Neurosciences, “G. d'Annunzio” University of Chieti, Chieti, Italy

3. Department of Biomorphology, Chieti, Italy, “G. d'Annunzio” University of Chieti, Chieti, Italy

4. Department of Biomedical Sciences, “G. d'Annunzio” University of Chieti, Chieti, Italy

Abstract

In 1997 a novel virus in the serum of a patient with acute post-transfusion hepatitis of non A-G etiology was identified. This agent was designed TT virus (TTV). It produces persistent viremia and no disease, but the mechanism of its persistence is poorly understood. In the present study mRNA expression of antiviral proteins as MxA, 2′5′ OAS, anti-apopotic protein, cytokines IL- 28, IL- 29 and IFN are examined in a subject affected by B lymphoma and positive for TTV DNA and RNA in this cellular subset, and in BJAB and Dohh2 cell lines.

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/039463200702000205

Reference35 articles.

1. A Novel DNA Virus (TTV) Associated with Elevated Transaminase Levels in Posttransfusion Hepatitis of Unknown Etiology

2. Human Circovirus TT Virus Genotype 6 Expresses Six Proteins following Transfection of a Full-Length Clone

3. Isolation of Multiple TT Virus Genotypes from Spleen Biopsy Tissue from a Hodgkin's Disease Patient: Genome Reorganization and Diversity in the Hypervariable Region

4. The role of TT virus infection in acute viral hepatitis

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