Nuclear Protein Kinase C-δ: A Possible Check-Point of Cell Cycle Progression-Reference-Cited by-同舟云学术

Nuclear Protein Kinase C-δ: A Possible Check-Point of Cell Cycle Progression

Published:2006-04 Issue:2 Volume:19 Page:287-291
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Marchisio M.¹²,Bertagnolo V.³,Lanuti P.¹²,Gaspari A.R.¹²,Paludi M.¹²,Ciccocioppo F.¹²,Ercolino E.¹²,Bascelli A.¹²,Cataldi A.¹,Miscia S.¹²

Affiliation:

1. Cell Signalling Unit at the Department of Biomorphology, University of Chieti-Pescara, Chieti

2. Fondazione “Università G. d'Annunzio”, Ce.S.I., Chieti

3. Cell Signalling Unit, Department of Morphology and Embryology, University of Ferrara, Italy

Abstract

Protein kinase Cs (PKCs) belong to a serine/threonine kinase family, ubiquitously expressed and claimed to be involved in physiological processes including apoptosis, cell growth and differentiation. The question of the subcellular localization and activity of PKCs remains to be clarified. Here we report that nuclear PKC-δ cooperates to regulate the S-G2/M phase transition of cell cycle, apparently being associated to chromosome condensation and alignment on the metaphase plate.

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/039463200601900206

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