Vitamins and Mast Cells-Reference-Cited by-同舟云学术

Vitamins and Mast Cells

Published:2010-10 Issue:4 Volume:23 Page:991-996
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Anogeianaki A.,Castellani M.L.¹,Tripodi D.²,Toniato E.¹,De Lutiis M.A.³,Conti F.⁴,Felaco P.³,Fulcheri M.⁵,Theoharides T.C.⁶,Galzio R.⁷,Caraffa A.⁸,Antinolfi P.⁸,Cuccurullo C.⁹,Ciampoli C.⁹,Felaco M.³,Cerulli G.⁸,Pandolfi F.¹⁰,Sabatino G.⁴,Neri G.¹¹,Shaik-Dasthagirisaheb Y.B.¹²

Affiliation:

1. Immunology Division, University of Chieti, Chieti, Italy

2. School of Dentistry, University of Chieti, Italy

3. Department of Human Dynamics, University of Chieti, Italy

4. Gynecology Division, University of Chieti, Italy

5. Department of Clinical Psychology, University of Chieti, Italy

6. Department of Pharmacology and Experimental Therapeutics, Biochemistry and Internal Medicine Tufts University School of Medicine, Tufts-New England Medical Center, Boston, MA, USA

7. Department of Health Sciences, University of L'Aquila, Italy

8. Orthopaedics Division, University of Perugia, Perugia, Italy

9. Institute of Internal Medicine, University of Chieti, Italy

10. Institute of Internal Medicine, Catholic University, Rome, Italy

11. Department of ORL, University of Chieti, Chieti, Italy

12. Department of Medicine, Boston University School of Medicine, Boston, MA, USA

Abstract

The immune system is a highly complex, intricately regulated group of cells whose integrated function is essential to health. The mast cell inflammatory response is characterized by an early phase with massive discharge of mediators stored in cytoplasmic secretory granules. Through multigranular/compound exocytosis and a late phase that involves generation of arachidonic acid metabolites and de novo synthesis of cytokines/chemokines and growth factors. Vitamins have been shown to have a protective effect on the body's immune cells. Vitamin C and E are necessary in allergic disease treatment where mast cells are involved. In addition, ascorbic acid and pyridoxine are useful compounds for the treatment of inflammatory disorder of the respiratory airways. Here we revisited the inter-relationship between vitamins and mast cells.

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/039463201002300403

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