Overuse of Prescription and OTC Non-Steroidal Anti-Inflammatory Drugs in Patients with Rheumatoid Arthritis and Osteoarthritis-Reference-Cited by-同舟云学术

Overuse of Prescription and OTC Non-Steroidal Anti-Inflammatory Drugs in Patients with Rheumatoid Arthritis and Osteoarthritis

Published:2013-01 Issue:1 Volume:26 Page:279-281
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Cavagna L.¹,Caporali R.¹,Trifirò G.²,Arcoraci V.²,Rossi S.¹,Montecucco C.¹

Affiliation:

1. Division of Rheumatology, University and IRCCS Foundation Policlinico S. Matteo, Pavia, Italy

2. Department of Clinical and Experimental Medicine and Pharmacology, University of Messina, Italy

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) have been demonstrated to have significant cardiovascular and gastrointestinal toxicity; high dose of intake and concomitant use of multiple compounds or corticosteroids are factors that increase the risk of NSAID toxicity. In this paper we described our experience on NSAIDs misuse (both prescribing and OTC formulations), particularly relevant in the setting of rheumatoid arthritis (39.5% of patients) and osteoarthritis (47% of patients). We also evaluated causes underlying NSAIDs misuse (e.g. not satisfactory pain control, other painful conditions, etc).

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/039463201302600132

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