Antibacterial Activity of Methyl Aminolevulinate Photodynamic Therapy in the Treatment of a Cutaneous Ulcer-Reference-Cited by-同舟云学术

Antibacterial Activity of Methyl Aminolevulinate Photodynamic Therapy in the Treatment of a Cutaneous Ulcer

Published:2011-07 Issue:3 Volume:24 Page:793-795
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Devirgiliis V.¹,Panasiti V.¹,Fioriti D.²,Anzivino E.³,Bellizzi A.³,Cimillo M.¹,Curzio M.¹,Melis L.¹,Roberti V.¹,Gobbi S.¹,Lieto P.¹,Richetta A.G.¹,Calvieri S.¹,Chiarini F.³,Nicosia R.³,Pietropaolo V.³⁴

Affiliation:

1. Department of Dermatology, “Sapienza” University Rome, Italy

2. National Institute for Infectious Diseases “Lazzaro Spallanzani”, Laboratory of Clinical Biochemistry and Pharmacology, Rome, Italy

3. Department of Health Sciences and Infectious Diseases, “Sapienza” University, Rome, Italy

4. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania, USA

Abstract

We describe a 79-year-old female with a chronic venous ulceration infected by Staphylococcus aureus and Enterococcus faecalis and not responsive to conventional treatments. The patient was treated with Methyl-Aminolaevulinate Photodynamic Therapy (MAL-PDT). After four weeks the cutaneous swabs become negative and we observed a significant clinical improvement. Therefore we suppose that MAL-PDT could represent a valid therapeutic option in the treatment of infected chronic ulcers.

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/039463201102400326

Reference10 articles.

1. Anti-microbial photodynamic therapy: useful in the future?

2. Antibacterial photodynamic therapy in dermatology

3. Basic principles of photodynamic therapy

4. Photodynamic therapy in the treatment of microbial infections: Basic principles and perspective applications

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