Inflammatory markers and suicidal attempts in depressed patients: A review-Reference-Cited by-同舟云学术

Inflammatory markers and suicidal attempts in depressed patients: A review

Published:2016-07-07 Issue:4 Volume:29 Page:583-594
ISSN:2058-7384
Container-title:International Journal of Immunopathology and Pharmacology
language:en
Short-container-title:Int J Immunopathol Pharmacol

Author:

Marini Stefano¹,Vellante Federica¹,Matarazzo Ilaria¹,De Berardis Domenico¹²,Serroni Nicola²,Gianfelice Daniela²,Olivieri Luigi²,Di Renzo Fulvia²,Di Marco Anna²,Fornaro Michele³,Orsolini Laura⁴⁵,Valchera Alessandro⁶,Iasevoli Felice⁷,Mazza Monica⁸,Perna Giampaolo⁹¹⁰¹¹,Martinotti Giovanni¹,Di Giannantonio Massimo¹

Affiliation:

1. Department of Neurosciences and Imaging, Chair of Psychiatry, University “G. D’Annunzio”, Chieti, Italy

2. NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital “G. Mazzini”, ASL 4 Teramo, Italy

3. Department of “Scienze della Formazione”, University of Catania, Italy

4. United Hospitals, Academic Department of Experimental and Clinical Medicine, Polytechnic University of Marche, Ancona, Italy

5. School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Herts, UK

6. Villa S. Giuseppe Hospital, Hermanas Hospitalarias, Ascoli Piceno, Italy

7. Laboratory of Molecular Psychiatry and Psychopharmacotherapeutics, Section of Psychiatry, Department of Neuroscience, University School of Medicine “Federico II”, Naples, Italy

8. Department of Health Science, University of L’Aquila, L’Aquila, Italy

9. Hermanas Hospitalarias, Department of Clinical Neurosciences, Villa San Benedetto Menni, Albese con Cassano, Como, Italy

10. Department of Psychiatry and Behavioral Sciences, Leonard Miller School of Medicine, University of Miami, Florida, USA

11. Department of Psychiatry and Neuropsychology, University of Maastricht, The Netherlands

Abstract

Major depressive disorder is a chronic and invalidating psychiatric illness and is associated with a greater risk of suicidal behaviors. In recent decades many data have supported a biological link between depressive states and inflammation. Pro-inflammatory cytokines have been found to rise, first of all TNF-α and IL-6. Suicidal behaviors have been consistently associated with increased levels of IL-6 and decreased levels of IL-2. The aim of this review is to investigate the relationship between inflammatory markers in depressed patients with or without suicidal attempts compared to healthy controls.

Publisher

SAGE Publications

Subject

Pharmacology,Immunology,Immunology and Allergy

Link

http://journals.sagepub.com/doi/pdf/10.1177/0394632015623793

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