Changes in Device Uptake and Glycemic Control Among Pregnant Women With Type 1 Diabetes: Data From the T1D Exchange

Author:

Levy Carol J.1ORCID,Foster Nicole C.2ORCID,DuBose Stephanie N.2ORCID,Agarwal Shivani3,Lyons Sarah K.4,Peters Anne L.5,Uwaifo Gabriel I.6,DiMeglio Linda A.7,Sherr Jennifer L.8,Polsky Sarit9ORCID

Affiliation:

1. Icahn School of Medicine at Mount Sinai, NY, USA

2. Jaeb Center for Health Research, Tampa, FL, USA

3. Fleischer Institute of Diabetes and Metabolism, Center for Diabetes Translational Research, Albert Einstein College of Medicine, Bronx, NY, USA

4. Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, USA

5. Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA

6. Ochsner Medical Center, New Orleans, LA, USA

7. Indiana University, School of Medicine, Indianapolis, IN, USA

8. Yale School of Medicine, New Haven, CT, USA

9. Barbara Davis Center for Diabetes, Aurora, CO, USA

Abstract

Objectives: To examine changes in device use and glycemic outcomes for pregnant women from the T1D Exchange Clinic Registry between the years 2010-2013 and 2016-2018. Methods: Participant-reported device use and glycemic outcomes were compared for women aged 16-40 years who were pregnant at the time of survey completion, comparing 2010-2013 (cohort 1) and 2016-2018 (cohort 2). Hemoglobin A1c results within 30 days prior to survey completion were obtained from medical records. Results: There were 208 pregnant women out of 5,236 eligible participants completing the questionnaire in cohort 1 and 47 pregnant women out of 2,818 eligible participants completing the questionaire in cohort 2. Continuous glucose monitor (CGM) use while pregnant trended upward among cohort 2 (70% vs 37%, P = .02), while reported continuous subcutaneous insulin infusion (CSII) use while pregnant declined (76% vs 64%, P = .04). HbA1c levels trended downward (6.8% cohort 1 vs 6.5% cohort 2, P = .07). Conclusions: Self-reported CGM use while pregnant increased over the studied intervals whereas CSII use decreased. Additional evaluation of device use and the potential benefits for T1D pregnancies is needed.

Funder

Leona M. and Harry B. Helmsley Charitable Trust

Publisher

SAGE Publications

Subject

Biomedical Engineering,Bioengineering,Endocrinology, Diabetes and Metabolism,Internal Medicine

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