I markers biologici. Introduzione:Biological markers. Introduction

Author:

Ferrari P.1,Ferrari G.1,Castagnetti G.1,Dotti A.1,Baisi B.1,Galizia G.1

Affiliation:

1. Divisione Urologica - Ospedale Civile - Modena

Abstract

Molecular biology has made giant strides over the last ten years and provides an immense field of research. The Authors first review the concepts of neoplastic proliferation and transformation of the phenotype, analysing cell constitution and its relations with the intercellular space. The most important moment in molecular research was the identification of the growth factors and consequently the process of transduction of signals from the outside into the cell and the retroinhibiting mechanisms of the same signals. The terms oncogene and antioncogene are defined as well as their most significant expressions.

Publisher

SAGE Publications

Subject

General Medicine

Reference30 articles.

1. KleinG., KleinE.: Mammary cancer. SeveriL. ed. Perugia, 713–717, 1958.

2. Pericellular Matrix in Malignant Transformation

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