IL-12 Administration Accelerates Autoimmune Diabetes in Both Wild-Type and IFN-γ-Deficient Nonobese Diabetic Mice, Revealing Pathogenic and Protective Effects of IL-12-Induced IFN-γ-Reference-Cited by-同舟云学术

IL-12 Administration Accelerates Autoimmune Diabetes in Both Wild-Type and IFN-γ-Deficient Nonobese Diabetic Mice, Revealing Pathogenic and Protective Effects of IL-12-Induced IFN-γ

Published:2003-06-01 Issue:11 Volume:170 Page:5491-5501
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J Immunol

Author:

Trembleau Sylvie,Penna Giuseppe,Gregori Silvia,Giarratana Nadia,Adorini Luciano

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference73 articles.

1. Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

2. The Murine Autoimmune Diabetes Model: NOD and Related Strains

3. The NOD mouse model of type 1 diabetes: As good as it gets?

4. Adoptive Transfer of Diabetes Into Immunodeficient NOD-scid/scid Mice: Relative Contributions of CD4+ and CD8+ T-Cells From Diabetic Versus Prediabetic NOD.NON-Thy-1a Donors

5. Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice.

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