Integrating Signals from IFN-γ and IL-4 by B Cells: Positive and Negative Effects on CD40 Ligand-Induced Proliferation, Survival, and Division-Linked Isotype Switching to IgG1, IgE, and IgG2a
Author:
Affiliation:
1. *Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Australia;
2. †Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT; and
3. ‡Medical Foundation, University of Sydney, Sydney, Australia
Abstract
Publisher
The American Association of Immunologists
Subject
Immunology,Immunology and Allergy
Link
https://journals.aai.org/jimmunol/article-pdf/163/8/4175/1109924/im209904175p.pdf
Reference32 articles.
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2. Finkelman, F. D., J. Holmes, I. M. Katona, J. F. Urban, Jr, M. P. Beckmann, L. S. Park, K. A. Schooley, R. L. Coffman, T. R. Mosmann, W. E. Paul. 1990. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8: 303
3. Paul, W. E.. 1987. Interleukin 4/B cell stimulatory factor 1: one lymphokine, many functions. FASEB J. 1: 456
4. Paul, W. E.. 1991. Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 77: 1859
5. Snapper, C. M., F. D. Finkelman, W. E. Paul. 1988. Regulation of IgG1 and IgE production by interleukin 4. Immunol. Rev. 102: 51
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