Mouse Cell Surface Antigens: Nomenclature and Immunophenotyping

Author:

Lai Lily1,Alaverdi Noosheen1,Maltais Lois2,Morse Herbert C.3

Affiliation:

1. *PharMingen, San Diego, CA 92121;

2. †Nomenclature Coordinator/Mouse Genome, The Jackson Laboratory, Bar Harbor, ME 04609; and

3. ‡Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892

Abstract

AbstractThis paper reviews cell surface Ags expressed on mouse hemopoietic and nonhemopoietic cells. The review will cover molecules included in the cluster of differentiation (CD) from CD1 to CD166 and lymphocyte Ag (Ly) series from Ly-1 to Ly-81 as well as some new Ags without current CD or Ly assignments. In addition to an update on mouse nomenclature, there will be a discussion of some known functions of the molecules and brief comments on the use of particular Ags for immunophenotyping of cell subsets. Several novel markers mentioned may prove useful in mouse immunology research.

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference57 articles.

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3. Schlossman, S. F., L. Bloumsell, W. Gilks, J. M. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. L. Silverstein, T. A. Springer, T. F. Tedder, R. F. Todd. 1995. Leucocyte Typing V: White Cell Differentiation Antigens Oxford University Press, New York.

4. Lai, L., N. Alaverdi, Z. Chen, F. G. M. Kroese, N. A. Bos, E. C.-M. Huang. 1996. Monoclonal antibodies to human, mouse, and rat cluster of differentiation (CD) antigens. Weir’s Handbook of Experimental Immunology 5th Ed.61.1. Blackwell Science, New York.

5. Ballas, Z. K., W. Rasmussen. 1993. Lymphokine-activated killer cells. VII. IL-4 induces an NK1.1+CD8α+β− TCR-αβ B220+ lymphokine-activated killer subset. J. Immunol. 150: 17

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