Quantifying Thymic Export: Combining Models of Naive T Cell Proliferation and TCR Excision Circle Dynamics Gives an Explicit Measure of Thymic Output
Author:
Publisher
The American Association of Immunologists
Subject
Immunology,Immunology and Allergy
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1. The Involution of the Ageing Human Thymic Epithelium is Independent of Puberty.
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3. Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
4. Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection
5. Decline in excision circles requires homeostatic renewal or homeostatic death of naive T cells
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