CD4+T Cells from (New Zealand Black × New Zealand White)F1Lupus Mice and Normal Mice Immunized Against Apoptotic Nucleosomes Recognize Similar Th Cell Epitopes in the C Terminus of Histone H3-Reference-Cited by-同舟云学术

CD4+T Cells from (New Zealand Black × New Zealand White)F1Lupus Mice and Normal Mice Immunized Against Apoptotic Nucleosomes Recognize Similar Th Cell Epitopes in the C Terminus of Histone H3

Published:2003-07-15 Issue:2 Volume:171 Page:636-644
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J Immunol

Author:

Fournel Sylvie,Neichel Sarah,Dali Hayet,Farci Sandrine,Maillère Bernard,Briand Jean-Paul,Muller Sylviane

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

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1. Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.

2. Nucleosome-restricted antibodies are detected before anti-dsdna and/or antihistone antibodies in serum of mrl-mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria

3. Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo.

4. Review: Nephritogenic autoantibodies in lupus: Current concepts and continuing controversies

5. Significance of anti-nuclear and anti-extracellular matrix autoantibodies for albuminuria in murine lupus nephritis; a longitudinal study on plasma and glomerular eluates in MRL/l mice

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