Unraveling the Arthus Mystery: Fc Receptors and the Holy Grail of Inflammation

Author:

Nimmerjahn Falk1,Cooper Max D.2ORCID

Affiliation:

1. *Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany; and

2. †Department of Pathology and Laboratory Medicine, Emory University School of Medicine and Emory Vaccine Center, Atlanta, GA

Abstract

Abstract This Pillars of Immunology article is a commentary on “Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade,” a pivotal article written by D. L. Sylvestre and J. V. Ravetch, and published in Science, in 1994. https://www.science.org/doi/10.1126/science.8066448.

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference21 articles.

1. Fcgamma receptors: old friends and new family members.;Nimmerjahn;Immunity,2006

2. The role of complement in inflammation and adaptive immunity.;Barrington;Immunol. Rev.,2001

3. Mechanisms of autoantibody-induced pathology.;Ludwig;Front. Immunol.,2017

4. Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade.;Sylvestre;Science,1994

5. Injections repetees de serum de cheval chez la lapin.;Arthus;CR Seances Soc. Biol. Fil.,1903

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