Therapeutic Small Interfering RNA Targeting Complement C3 in a Mouse Model of C3 Glomerulopathy
Author:
Affiliation:
1. *Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Centro Anna Maria Astori, Bergamo, Italy; and
2. †Silence Therapeutics GmbH, Berlin, Germany
Abstract
Publisher
The American Association of Immunologists
Subject
Immunology,Immunology and Allergy
Link
https://journals.aai.org/jimmunol/article-pdf/208/7/1772/1487790/ji2100730.pdf
Reference31 articles.
1. C3 glomerulopathy: consensus report.;Pickering;Kidney Int.,2013
2. C3 glomerulopathy - understanding a rare complement-driven renal disease.;Smith;Nat. Rev. Nephrol.,2019
3. Update on C3 glomerulopathy: a complement-mediated disease.;Caravaca-Fontán;Nephron,2020
4. Autoimmune abnormalities of the alternative complement pathway in membranoproliferative glomerulonephritis and C3 glomerulopathy.;Noris;Pediatr. Nephrol.,2019
5. C3 glomerulopathy: clinicopathologic features and predictors of outcome.;Medjeral-Thomas;Clin. J. Am. Soc. Nephrol.,2014
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1. C3 Glomerulopathy: Novel Treatment Paradigms;Kidney International Reports;2023-12
2. Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease;Frontiers in Immunology;2023-09-15
3. Liver factor B silencing to cure C3 glomerulopathy: Evidence from a mouse model of complement dysregulation;Molecular Immunology;2023-09
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