Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells

Author:

Penaranda Cristina,Tang Qizhi,Bluestone Jeffrey A.

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference37 articles.

1. CD3-specific antibodies: a portal to the treatment of autoimmunity

2. Immunologic monitoring with monoclonal antibodies to human T-cell subsets.;Cosimi;Transplant. Proc.,1981

3. RELEASE OF TUMOR NECROSIS FACTOR, INTERLEUKIN-2, AND GAMMA-INTERFERON IN SERUM AFTER INJECTION OF OKT3 MONOCLONAL ANTIBODY IN KIDNEY TRANSPLANT RECIPIENTS

4. Systemic Reaction to the Anti–T-Cell Monoclonal Antibody OKT3 in Relation to Serum Levels of Tumor Necrosis Factor and Interferon-α

5. An anti-murine CD3 monoclonal antibody with a low affinity for Fcγ receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.;Alegre;J. Immunol.,1995

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