Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors

Abstract

IntroductionThe objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors.Material and methodsA total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). We analyzed 398 women from 723 patients.ResultsOverall survival analysis was conducted for both groups, separately and combined. Patients with BC aged > 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients <50 years of age.ConclusionsAge > 65 years is a negative prognostic factor independent of other factors.