Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic-Reference-Cited by-同舟云学术

Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic

Published:2022-08-30 Issue:5 Volume:18 Page:1395-1398
ISSN:1734-1922
Container-title:Archives of Medical Science
language:
Short-container-title:Arch Med Sci

Author:

Mihalčin Matúš¹²^ORCID,Husova Libuse³^ORCID,Vasickova Petra⁴^ORCID,Bena Marcel⁴^ORCID,Husa Petr¹²^ORCID

Affiliation:

1. Department of Infectious Diseases, Faculty of Medicine, Masaryk University, Brno, Czech Republic

2. Department of Infectious Diseases, University Hospital Brno, Brno, Czech Republic

3. Centre of Cardiovascular and Transplant Surgery Brno, Brno, Czech Republic

4. Veterinary Research Institute, Brno, Czech Republic

Abstract

IntroductionThe majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic.Material and methodsThe retrospective analysis of 173 patients with HE.ResultsAt least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE.ConclusionsThere is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

Publisher

Termedia Sp. z.o.o.

Subject

General Medicine

Link

https://www.archivesofmedicalscience.com/pdf-152338-78030

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