Association between air pollution and bone mineral density: a Mendelian randomization study-Reference-Cited by-同舟云学术

Association between air pollution and bone mineral density: a Mendelian randomization study

Published:2024-08-28 Issue: Volume: Page:
ISSN:1734-1922
Container-title:Archives of Medical Science
language:
Short-container-title:Arch Med Sci

Author:

Jiang Rui¹²,Qu Qi²³,Wang Zhiyu²³,Luo Feng⁴,Mou Shuanglin²

Affiliation:

1. Graduate school, Hubei University of Traditional Chinese Medicine, Wuhan, China

2. Department of Orthopedics, Huanggang Hospital of Traditional Chinese Medicine, Huanggang, China

3. Medical College, Hubei Minzu University, Enshi, China

4. Department of Rehabilitation, Huanggang Central Hospital, Huanggang, China

Abstract

IntroductionThe association of air pollution with bone mineral density (BMD) has attracted increasing attention. However, establishing a causal relationship remains uncertain.MethodsWe conducted a Mendelian randomization (MR) study employing PM2.5, PM2.5-10, PM10, nitrogen dioxide, and nitrogen oxides as exposures and BMD as the outcome to explore the causality between air pollution and the occurrence of decreased BMD.ResultsBy employing the IVW method, we identified a negative causality between air pollution (PM2.5, PM10, and nitrogen oxides) and BMD.ConclusionsOur findings demonstrate that PM2.5, PM10 and nitrogen oxides exposure may contribute to decreased BMD.

Publisher

Termedia Sp. z.o.o.

Link

https://www.archivesofmedicalscience.com/pdf-192628-113418

Reference14 articles.

1. Harvey N, Dennison E, Cooper C. Osteoporosis: impact on health and economics. Nat Rev Rheumatol 2010; 6: 99-105.

2. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res 2007; 22: 465-75.

3. Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature 2018; 561: 45-56.

4. Goshua A, Akdis CA, Nadeau KC. World Health Organization global air quality guideline recommendations: Executive summary. Allergy 2022; 77: 1955-60.

5. Arias-Perez RD, Taborda NA, Gomez DM, Narvaez JF, Porras J, Hernandez JC. Inflammatory effects of particulate matter air pollution. Environ Sci Pollut Res Int 2020; 27: 42390-404.