Use of a pentoxifylline-tocopherol-clodronate combination (PENTOCLO) for a patient with osteoradionecrosis of the mandible
Author:
Affiliation:
1. Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine
2. Department of Oral and Maxillofacial Surgery, Kanagawa Cancer Center
Publisher
Japanese Society of Oral and Maxillofacial Surgeons
Subject
Industrial and Manufacturing Engineering,Environmental Engineering
Link
https://www.jstage.jst.go.jp/article/jjoms/66/12/66_610/_pdf
Reference27 articles.
1. 3) Suh JD, Blackwell KE, et al : Disease relapse after segmental resection and free flap reconstruction for mandibular osteoradionecrosis. Otolaryngol Head Neck Surg 142: 586-591, 2010.
2. 4) Marx R and Johnson R : Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg Oral Med Oral Pathol 64: 379-390, 1987.
3. 5) Delanian S and Lefaix JL : The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol 73: 119-131, 2004.
4. 6) Delanian S, Chatel C, et al : Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocoperol-clodronate combination (PENTOCLO) : A phase II trial. Int J Radiat Oncol Biol Phys 80: 832-839, 2011.
5. 7) Lapa C, Linz C, et al : Three-phase bone scintigraphy for imaging osteoradionecrosis of the jaw. Clin Nucl Mes 39: 21-25, 2014.
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1. A clinical study of surgical treatment for osteoradionecrosis of the jaw;Journal of Japanese Society of Oral Oncology;2021
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