A New Biomarker in The Distinction Between Stable Coronary Artery Disease and Acute Coronary Syndrome:Thiols-Reference-Cited by-同舟云学术

A New Biomarker in The Distinction Between Stable Coronary Artery Disease and Acute Coronary Syndrome:Thiols

Published:2022-06-01 Issue:4 Volume:12 Page:1-6
ISSN:2667-7180
Container-title:Journal of Contemporary Medicine
language:en
Short-container-title:J Contemp Med

Author:

YILMAZ Yücel¹,KELEŞOĞLU Şaban²,TEKİN Kemal³,ÇALAPKORUR Bekir³,EREL Özcan⁴,NEŞELİOĞLU Salim⁴,ELCİK Deniz²

Affiliation:

1. Kayseri City Training and Research Hospital, Department of Cardiology

2. ERCIYES UNIVERSITY, SCHOOL OF MEDICINE

3. SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KAYSERİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ

4. YILDIRIM BEYAZIT UNIVERSITY, SCHOOL OF MEDICINE

Abstract

Backraund; Thiols are important elements for oxidation reactions and under oxidative stress. The aim of this study was to determine thiole levels, an antioxidative marker in CAD patients with stable and acute coronary syndrome. Methods; 210 of the patients included in the study were diagnosed with acute coronary syndrome (ACS), 205 consisted of patients with stable angina pectoris (SAP). Thiol groups levels and thiol/disulphide homeostasis was measured by spectrophotometrically. Results: Native thiol and total thiol levels, disulfide/natural thiol and disulfide/total thiol ratios were decreased in the ACS groups compared to the SAP groups Conclusions: Thiol levels and thiol / disulfide ratios can be used as markers to evaluate acute coronary syndrome.

Publisher

Cagdas Tip Dergisi: Journal of Contemporary Medicine

Subject

General Medicine

Reference45 articles.

1. 1. Pathak LA, Shirodkar S, Ruparelia R and Rajebahadur J: Coronary artery disease in women. Indian Heart J. 2017; 69: 532-8.

2. 2. Badimon L and Vilahur G: Thrombosis formation on atherosclerotic lesions and plaque rupture. J Intern Med. 2014; 276: 618-32.

3. 3. Vogiatzi G, Tousoulis D and Stefanadis C: The role of oxidative stress in atherosclerosis. Hellenic J Cardiol. 2009; 50: 402-9.

4. 4. Bonomini F, Tengattini S, Fabiano A, Bianchi R and Rezzani R: Atherosclerosis and oxidative stress. Histol Histopathol. 2008; 23: 381-90.

5. 5. Stocker R and Keaney JF: Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004 ; 84: 1381-478.