Klinik Parametrelerin Ülseratif Kolit Seyrinde Atak Sayılarına Etkisinin Karşılaştırılması: Tek Merkezli Çalışma

Abstract

Aim: The aim of this study was to find the factors affecting the frequency of attacks of patients diagnosed with ulcerative colitis (UC). Method: In our single-center retrospective descriptive study, 40 UC patients who admitted to our hospital for follow-up from January 2021 to December 2022. The baseline demographic and clinical characteristics, laboratory values and, treatments during the disease course were compared among patients with number of attacks < 2 per year ( Group1) and number of attacks ≥2 per year ( Group 2). Results: There were 25 (male∕female:11∕14) patients in Group 1 and 15 (male∕female:7∕8) patients in Group 2. No statistically significant difference was found between the mean age, sex, age of diagnosis, duration of disease, co-morbidities and extraintestinal involvement of both groups. The median CRP values were significantly higher in the Group 2, compared to the group 1 (P = 0.04). There was statistically significant differences between groups in terms of endoscopic severe activity (12% vs, 40%; p