Author:
Mahmood Ammar A. Razzak,Al-Juboori Sahar B.
Abstract
Saccharin is firstly synthesized in 1879. It is a very well-known as an inexpensive substitute for sugar as it is a non-caloric sweetener. The article shows the properties, use, metabolism and various synthesis and reactions of saccharine. Moreover, the toxicological reports explain that saccharin is mostly responsible for the bladder tumors observed in the male rats, the relationship between the consumption of saccharin and bladder cancer is afforded by epidemiological studies. The benefit-risk evaluation for saccharin is hardly to indicate. Saccharin is a sugar substitute, frequently used either in food industry, or in pharmaceutical formulations and even in tobacco products. The chemistry of saccharin is interesting because of it suspected carcinogenous character and the possible use as an antidote for metal poisoning. It appears prudent to evaluate their main properties and applications further.
Publisher
College of Education for Pure Sciences Ibn Al-Haitham
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Artificial Sweetener Consumption Increasing Type II Diabetes Risk Revealed by Gut Microbiome;Highlights in Science, Engineering and Technology;2023-09-20
2. In Situ Co-Amorphization of Olanzapine in the Matrix and on the Coat of Pellets;Pharmaceutics;2022-11-24
3. Synthesis, Anticancer, Antioxidant, Anti-Inflammatory, Antimicrobial Activities, Molecular Docking, and DFT Studies of Sultams Derived from Saccharin;Molecules;2022-10-20
4. Novel saccharin analogs as promising antibacterial and anticancer agents: synthesis, DFT, POM analysis, molecular docking, molecular dynamic simulations, and cell-based assay;Frontiers in Pharmacology;2022-10-04
5. Optimisation of the ingredients for the development of low-calorie basundi;Indian Journal of Dairy Science;2022-04-20