Effects of an oriental herbal medicine, “Saiboku-to”, and its constituent herbs on Compound 48/80-induced histamine release from peritoneal mast cells in rats

Author:

Ikarashi Y.,Yuzurihara M.,Sakakibara I.,Takahashi A.,Ishimaru H.,Maruyama Y.

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference24 articles.

1. Autoregulation of histamine release in brain by presynaptic H3 receptors;Arrang;Neurosci.,1985

2. Neurotensin stimulation of mast cell secretion is receptor-mediated, pertusis-toxin sensitive and requires activation of phospholipase C;Barrocas;Immunopharmacol,1999

3. Suppression of Saiboku-to of antigen-induced Ca2+ influx into mast cells;Dobashi;Kampo and Immunoallergy,1993

4. Compound 48/80 is a selective and powerful inhibitor of calmodulin-regulated functions;Gietzen;Biochim. Biophys. Acta.,1983

5. Ikarashi, Y., Yuzurihara, M., Maruyama, Y. Inhibition of gastric acid secretion by Saiboku-to, an oriental herbal medicine, in rats. Dig. Dis. Sci. 2000a, in press

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