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Cyclosporine A and Tacrolimus: In vitro investigations on the differential interactions with the cytochrome P450 system in rat and human liver

  • Published:2003-01 Issue:5-6 Volume:54 Page:467-473
  • ISSN:0940-2993
  • Container-title:Experimental and Toxicologic Pathology
  • language:en
  • Short-container-title:Experimental and Toxicologic Pathology

Author:

Lupp Amelie,Kuhn Urs Dieter,Herwig Roland,Karge Elke,Rost Michael,Scheele Johannes,Fleck Christian

Publisher

Elsevier BV

Subject

Cell Biology,Toxicology,General Medicine,Pathology and Forensic Medicine

Reference45 articles.

1. A simple and sensitive assay of 7-ethoxycoumarin deethylation;Aitio;Anal Biochem,1978

2. Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes;Amacher;Toxicol Lett,1998

3. A comparison of the effects of cyclosporine (CsA) on hepatic microsomal drug metabolism in three different strains of rat;Augustine;Gen Pharmacol,1989

4. Selective suppression of rat hepatic microsomal activity during chronic cyclosporine nephrotoxicity;Brunner;J Pharmacol Exp Ther,1996

5. Cyclosporine suppresses rat hepatic cytochrome P450 in a time-dependent manner;Brunner;Kidney Int,1998

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